High Purity Lidocaine CAS 137-58-6 | Pharmaceutical Grade Chemicals Factory

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What is Lidocaine

Lidocaine was the first amino amide synthesized in 1948and has become the most widely used local anesthetic. Thetertiary amine has a pKa of 7.8 and it is formulated as thehydrochloride salt with a pH between 5.0 and 5.5. When lidocaineis formulated premixed with epinephrine the pH ofthe solution is adjusted to between 2.0 and 2.5 to prevent the hydrolysis of the epinephrine. Lidocaine is also availablewith or without preservatives. Some formulations of lidocainecontain a methylparaben preservative that maycause allergic reactions in PABA-sensitive individuals. Thelow pKa and medium water solubility provide intermediateduration of topical anesthesia of mucous membranes.Lidocaine can also be used for infiltration, peripheral nerveand plexus blockade, and epidural anesthesia.

Product Name	Lidocaine
Synonyms	2-(Diethylamino)-2',6'-acetoxylidide;2-(diethylamino)-2’,6’-acetoxylidide;2-(diethylamino)-n-(2,6-dimethylphenyl)-acetamid;2',6'-Acetoxylidide, 2-(diethylamino)-;6’-acetoxylidide,2-(diethylamino)-2;Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-;Ligoncaine;Maricaine
CAS	137-58-6
MF	C14H22N2O
MW	234.34
EINECS	205-302-8
Melting point	66-69°C
Boiling point	bp4 180-182°; bp2 159-160°
Density	0.9944 (rough estimate)
refractive index	1.5110 (estimate)
Fp	9℃
Storage temp.	Store at RT
Solubility	ethanol 4 mg/mL
Form	powder
Color	White to slightly yellow
Water Solubility	practically insoluble
Usage	Do not sell to personal,for research only
Storage	Keep in cool, dry place, tightly sealed container

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